0% 0 Pharmacology Quiz 2 1 / 50 Prolonged use of aspirin leads to______________? Bleeding defects A & B peptic ulcer Carcinoma 2 / 50 Drugs which cause ototoxicity and circumoral paraesthesia are______________? Chloramphenicol Antitubercular drugs Antileprotic drugs Streptomycin 3 / 50 Which of the following opioids is not given intrathecally ? Fentanyl Sufentanil Remifentanil Morphine 4 / 50 Amino glycosides_______________? Accumulate in renal failure Inhibit protein synthesis All of the above Effective against gram negative infection 5 / 50 Which one of the following drugs is not contraindicated in bronchial asthma ? Nitroglycerine Propanolol Stropine Morphine 6 / 50 Drugs like barbiturates precipitate symptoms of prophyria because______________? They inhibit heme oxygenase They induce heme oxygenase They depress ALA synthase They inhibit ALA synthase 7 / 50 Dissociative Sedation and analgesia described by Robert and Rosebaum in 1971 is____________? 20 to 30% N20 30 to 50% N20 50 to 70% N20 5 to 20% N20 8 / 50 Following drug which undergo most of its metabolism presystemically______________? Verapamil Propranolol Paracetamol Salbutamol 9 / 50 Drugs showing zero order kinetics of elimination_____________? Are more common than first order kinetics Decrease in concentration exponentially with time Show a plot of drug concentration versus time that is linear Have a half ? life independent of dose 10 / 50 A patient, without prior medication, breathes a gas mixture consisting of 50 percent nitrous oxide and 50 percent oxygen by volume. Which of the following effects would be expected_____________? Excitation Analgesia Surgical anesthesia Respiratory arrest 11 / 50 Less gastrointestinal bleed is seen in the following NSAID_______________? Meloxicam Ibuprofen Naproxen C0X2 specific inhibitors 12 / 50 The drug not belonging to amide group_______________? Xylocaine Procaine Bupivacaine Lignocaine 13 / 50 All of the following statements regarding biovailability of a drug are true except______________? Biovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration Biovailability can be determined from plasma concentration or urinary excretion data It is the proportion (fraction) of unchanged drug that reaches the systemic circulation Low oral biovailability always and necessarily mean poor absorption 14 / 50 The most common cause of antibiotic ? related diarrhea is____________? Shigella K.pneumoniae C.difficile H.pylori 15 / 50 During administration of NSAIDs in children, the most important of dose administration is______________? Nature of the drug Weight of the child Age of child Chronicity of pain 16 / 50 One of the drug is betalactamase inhibitor_____________? Pencillin G Cloxacillin Ampicillin Sulbactum 17 / 50 Omeprazol is used in the treatment of____________? Amoebiasis Malaria cholera Peptic Ulcer 18 / 50 Which of the following is a characteristic of tetracycline stains ? Is always accompanied by hypolastic defects Stained teeth fluoresce light yellow under U.V light There is less deposition in dentine as compared to enamel Stains are dark brown in color 19 / 50 Paracetamol is contraindicated in_______________? Chronic hepatitis A & B Nephritis Bleeding disorders 20 / 50 While performing a procedure, a resident doctor injures herself with a suture needle that has been used to stitch a patient with HIV infection for 11 years. He has been complaint with therapy for several years and has recently changed tablets because of alteration in his appearance. His last CD4 count was 360 cells/mm. The doctor is offered post exposure prophylaxis. Which regimen should she take ? Ziduvidine and Lamivudine and Stavudine Ziduvidine and Lamivudine and Abacavir Ziduvidine and Lamivudine and Indivair Ziduvidine and Lamivudine 21 / 50 Which of the following is caused by Amphotericin B____________? Hyponatremia Hypermagnesemia Hyperkalemia Hypo Kalemia 22 / 50 Which of the following exerts its major systemic pharmacological action when administered orally_____________? Chloral hydrate Insulin Procaine Streptomycin 23 / 50 Complete drug elimination occurs after how many hours, if t? is 4 hrs______________? 25 hrs 20 hrs 30 hrs 12 hrs 24 / 50 What is the advantage of sublingual route of administration of drugs_____________? Lipid soluble Can be spitted out with signs of toxicity prevents or bypasses first pass effects Easy to administer 25 / 50 Which drug causes photosensitivity______________? Penicillin Cephalosporin Aminoglycoside Tetracycline 26 / 50 In cirrhoses patients, dose reduction is needed for all the following drugs except_____________? Metronidazole Lorazepam Theophylline Paracetamol 27 / 50 Agents used by local application to control bleeding include all of the following except____________? Gelatin foam Adrenaline Trannic acid Vitamin-K 28 / 50 Following antimicrobials are termed as type I calcimimetics that mimic the stimulatory effect of calcium, on the calcium sensing receptor to inhibit PTH secretion by the parathyroid gland EXCEPT______________? Gentamicin Neomycin Streptomycin Hamycin 29 / 50 In the second stage of anesthesia the pupil is_______________? Normal in size Totally dilated Constricted Partially dilated 30 / 50 The oropharyngeal and oesophageal candidiasis following long-term therapy with a broad spectrum antibiotic can be best treated with____________? Fluconazole Griseofulvin Sulfonates Amphotericin 31 / 50 Gastric secretion has been shown to be most effectively reduced with the use of___________? Anticholinergic Adrenal steroids H1 histamine receptor antagonist H2 histamine receptor antagonist 32 / 50 Birbiturates in pediatrics is_____________? Can be used safely Contraindicated Not much use Low safety 33 / 50 Which among the following anti-HIV drugs is also used to treat viral hepatitis B ? Efavirenz Enfuvirtide Ritonavir Lamivudine 34 / 50 A patient with grandmal epilepsy would likely be under treatment with_______________? Phenytoin Pentobarbital Meprobamate Trimethadione 35 / 50 Serum sickness is caused by all the following drugs except_____________? Pencillins Aspirin Chloroquin Sulfonamides 36 / 50 Which of the following drug is given for treating hypertensive crisis_______________? Isosobide dinitrate Digoxin NIfedipine Verapamil 37 / 50 The most common side effect of the oral administration of ampicillin is_______________? Renal failure Oral candidiasis Diarrhoea Anaphylactic shock 38 / 50 Sildenafil is inhibitor of_______________? PDE-5 cAMP cGMP PGI2 39 / 50 All of the following are tocolytic except_______________? Isoxsuprine Natrexam Atosiban Ritodrine 40 / 50 All are true about metformin except_____________? Reduce hepatic glucose production Excreted unchanged in urine Inhibits cellular respiration in mitochondria Used in decompensated heart failure 41 / 50 Which of the following drugs is used to treat both diabetes mellitus and diabetes insipidus_____________? Glipizide Glibenclamide Chlorpropamide Glicazide 42 / 50 Which is NOT a 2nd generation antihistaminic ? Terfenidine Loratidine Acrivastatine Cyclizine 43 / 50 Mechanism of action of quinolones is______________? Inhibits bacterial cell wall synthesis Inhibits intake of folic acid Inhibits Bacterial protein synthesis Inhibits DNA gyrase 44 / 50 Aspirine is useful in all the following conditions EXCEPT_____________? Post myocardial infarction Gout Fever Venous thrombosis 45 / 50 Metronidazole is a type of___________? Imidazole derivative Antidepressant Broad spectrum antibiotic Quinolone 46 / 50 A patient on digoxin should not be given quindine because______________? Decreases the plasma potassium level Displaces digoxine from its tissue binding sites Decrease the renal clearance of digoxin Displaces digoxin from its protein binding sites 47 / 50 Ketamine is a________________? Antidepressive agent Hypnotic agent Local anesthetic agent Short general anesthetic agent 48 / 50 Which is not antiemetic ? Domperidone Phenazocine Cyclizine Ondanestron 49 / 50 A potent non-texic anti-herpes drug is_______________? Idoxyuridine Vidarabine Ara-amp Acyclovir 50 / 50 The drug which is contraindicated in haemophilla is_________________? Penicillinium Dipheny 1 hydantoin Amino epsilon caproic acid Aspirin Provide Your Information Your score is The average score is 0% LinkedIn Facebook Twitter 0% Restart quiz Send feedback Share on facebook Facebook Share on twitter Twitter Share on whatsapp WhatsApp PrevPharmacology Quiz 1 Pharmacology Quiz 3Next
