0% 0 Pharmacology Quiz 2 1 / 50 Sildenafil is inhibitor of_______________? PGI2 cGMP cAMP PDE-5 2 / 50 Prolonged use of aspirin leads to______________? Bleeding defects A & B peptic ulcer Carcinoma 3 / 50 The drug not belonging to amide group_______________? Xylocaine Procaine Lignocaine Bupivacaine 4 / 50 All are true about metformin except_____________? Reduce hepatic glucose production Excreted unchanged in urine Used in decompensated heart failure Inhibits cellular respiration in mitochondria 5 / 50 A patient with grandmal epilepsy would likely be under treatment with_______________? Meprobamate Trimethadione Phenytoin Pentobarbital 6 / 50 Which drug causes photosensitivity______________? Tetracycline Aminoglycoside Penicillin Cephalosporin 7 / 50 Mechanism of action of quinolones is______________? Inhibits bacterial cell wall synthesis Inhibits intake of folic acid Inhibits DNA gyrase Inhibits Bacterial protein synthesis 8 / 50 Which is NOT a 2nd generation antihistaminic ? Terfenidine Acrivastatine Cyclizine Loratidine 9 / 50 All of the following statements regarding biovailability of a drug are true except______________? Biovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration Biovailability can be determined from plasma concentration or urinary excretion data Low oral biovailability always and necessarily mean poor absorption It is the proportion (fraction) of unchanged drug that reaches the systemic circulation 10 / 50 A patient on digoxin should not be given quindine because______________? Displaces digoxine from its tissue binding sites Displaces digoxin from its protein binding sites Decreases the plasma potassium level Decrease the renal clearance of digoxin 11 / 50 Following drug which undergo most of its metabolism presystemically______________? Salbutamol Verapamil Propranolol Paracetamol 12 / 50 Omeprazol is used in the treatment of____________? Peptic Ulcer cholera Amoebiasis Malaria 13 / 50 Which of the following exerts its major systemic pharmacological action when administered orally_____________? Streptomycin Procaine Chloral hydrate Insulin 14 / 50 The oropharyngeal and oesophageal candidiasis following long-term therapy with a broad spectrum antibiotic can be best treated with____________? Amphotericin Griseofulvin Sulfonates Fluconazole 15 / 50 While performing a procedure, a resident doctor injures herself with a suture needle that has been used to stitch a patient with HIV infection for 11 years. He has been complaint with therapy for several years and has recently changed tablets because of alteration in his appearance. His last CD4 count was 360 cells/mm. The doctor is offered post exposure prophylaxis. Which regimen should she take ? Ziduvidine and Lamivudine and Stavudine Ziduvidine and Lamivudine and Abacavir Ziduvidine and Lamivudine and Indivair Ziduvidine and Lamivudine 16 / 50 Amino glycosides_______________? Inhibit protein synthesis All of the above Accumulate in renal failure Effective against gram negative infection 17 / 50 Gastric secretion has been shown to be most effectively reduced with the use of___________? Anticholinergic H2 histamine receptor antagonist Adrenal steroids H1 histamine receptor antagonist 18 / 50 Complete drug elimination occurs after how many hours, if t? is 4 hrs______________? 30 hrs 20 hrs 12 hrs 25 hrs 19 / 50 Which of the following drug is given for treating hypertensive crisis_______________? Digoxin Isosobide dinitrate Verapamil NIfedipine 20 / 50 Which one of the following drugs is not contraindicated in bronchial asthma ? Nitroglycerine Morphine Stropine Propanolol 21 / 50 A potent non-texic anti-herpes drug is_______________? Acyclovir Vidarabine Ara-amp Idoxyuridine 22 / 50 Which of the following drugs is used to treat both diabetes mellitus and diabetes insipidus_____________? Glicazide Chlorpropamide Glibenclamide Glipizide 23 / 50 The most common side effect of the oral administration of ampicillin is_______________? Renal failure Diarrhoea Anaphylactic shock Oral candidiasis 24 / 50 In cirrhoses patients, dose reduction is needed for all the following drugs except_____________? Paracetamol Lorazepam Metronidazole Theophylline 25 / 50 Dissociative Sedation and analgesia described by Robert and Rosebaum in 1971 is____________? 5 to 20% N20 50 to 70% N20 20 to 30% N20 30 to 50% N20 26 / 50 Ketamine is a________________? Short general anesthetic agent Hypnotic agent Local anesthetic agent Antidepressive agent 27 / 50 The most common cause of antibiotic ? related diarrhea is____________? K.pneumoniae Shigella C.difficile H.pylori 28 / 50 One of the drug is betalactamase inhibitor_____________? Ampicillin Sulbactum Cloxacillin Pencillin G 29 / 50 A patient, without prior medication, breathes a gas mixture consisting of 50 percent nitrous oxide and 50 percent oxygen by volume. Which of the following effects would be expected_____________? Surgical anesthesia Analgesia Excitation Respiratory arrest 30 / 50 Drugs like barbiturates precipitate symptoms of prophyria because______________? They depress ALA synthase They inhibit heme oxygenase They induce heme oxygenase They inhibit ALA synthase 31 / 50 In the second stage of anesthesia the pupil is_______________? Constricted Totally dilated Normal in size Partially dilated 32 / 50 Serum sickness is caused by all the following drugs except_____________? Chloroquin Aspirin Sulfonamides Pencillins 33 / 50 Paracetamol is contraindicated in_______________? Bleeding disorders Nephritis A & B Chronic hepatitis 34 / 50 Which among the following anti-HIV drugs is also used to treat viral hepatitis B ? Enfuvirtide Ritonavir Lamivudine Efavirenz 35 / 50 The drug which is contraindicated in haemophilla is_________________? Aspirin Amino epsilon caproic acid Penicillinium Dipheny 1 hydantoin 36 / 50 Which is not antiemetic ? Domperidone Cyclizine Ondanestron Phenazocine 37 / 50 Which of the following opioids is not given intrathecally ? Fentanyl Morphine Remifentanil Sufentanil 38 / 50 Aspirine is useful in all the following conditions EXCEPT_____________? Fever Gout Post myocardial infarction Venous thrombosis 39 / 50 Which of the following is a characteristic of tetracycline stains ? Is always accompanied by hypolastic defects Stained teeth fluoresce light yellow under U.V light Stains are dark brown in color There is less deposition in dentine as compared to enamel 40 / 50 Birbiturates in pediatrics is_____________? Not much use Contraindicated Can be used safely Low safety 41 / 50 Less gastrointestinal bleed is seen in the following NSAID_______________? C0X2 specific inhibitors Meloxicam Naproxen Ibuprofen 42 / 50 Following antimicrobials are termed as type I calcimimetics that mimic the stimulatory effect of calcium, on the calcium sensing receptor to inhibit PTH secretion by the parathyroid gland EXCEPT______________? Gentamicin Hamycin Neomycin Streptomycin 43 / 50 All of the following are tocolytic except_______________? Ritodrine Isoxsuprine Natrexam Atosiban 44 / 50 Drugs which cause ototoxicity and circumoral paraesthesia are______________? Antitubercular drugs Antileprotic drugs Chloramphenicol Streptomycin 45 / 50 Metronidazole is a type of___________? Imidazole derivative Quinolone Broad spectrum antibiotic Antidepressant 46 / 50 Which of the following is caused by Amphotericin B____________? Hypo Kalemia Hypermagnesemia Hyperkalemia Hyponatremia 47 / 50 Agents used by local application to control bleeding include all of the following except____________? Adrenaline Gelatin foam Vitamin-K Trannic acid 48 / 50 During administration of NSAIDs in children, the most important of dose administration is______________? Age of child Weight of the child Nature of the drug Chronicity of pain 49 / 50 What is the advantage of sublingual route of administration of drugs_____________? Can be spitted out with signs of toxicity Easy to administer Lipid soluble prevents or bypasses first pass effects 50 / 50 Drugs showing zero order kinetics of elimination_____________? Show a plot of drug concentration versus time that is linear Are more common than first order kinetics Decrease in concentration exponentially with time Have a half ? life independent of dose Provide Your Information Your score is The average score is 0% LinkedIn Facebook Twitter 0% Restart quiz Send feedback Share on facebook Facebook Share on twitter Twitter Share on whatsapp WhatsApp PrevPharmacology Quiz 1 Pharmacology Quiz 3Next
